This article is for informational purposes only and does not constitute medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. If you think you may have a medical emergency, call your doctor or 911 immediately.
Keck Medicine of USC has two locations in Pasadena, and they sit almost next door to each other on South Fair Oaks Avenue. The catch is that they do different things. Knowing whether your visit is at 590 or 625 S. Fair Oaks saves you a wrong turn on the day.
Both buildings bring USC’s specialists and services to the San Gabriel Valley. One is a large new imaging and treatment hub, and the other is a multispecialty clinic. This guide breaks down what lives where so you can head to the right door.
Two Buildings on South Fair Oaks Avenue
Because they are so close together, it is easy to mix them up. Always check your appointment details for the exact street number and suite. A quick look before you leave keeps the visit smooth.
Both sit near the corner of Fair Oaks Avenue and California Boulevard in south Pasadena. That puts them close to the 110 and 210 freeways for family and visitors. The shared stretch of street is part of why the two numbers get confused.
590 S. Fair Oaks Ave: Imaging and Advanced Care
This is the place for imaging and certain advanced treatments. Its imaging suite offers PET, MRI, CT, ultrasound, and X-ray, read by on-site radiologists. A wide-bore MRI helps people who feel closed in by standard scanners.
625 S. Fair Oaks Ave: Multispecialty Clinic
That multispecialty suite includes care such as dermatology, endocrinology, family medicine, gastroenterology, internal medicine, neurology, and ear, nose, and throat care. It is also home to the USC Roski Eye Institute for eye exams and eye conditions.
Why Keck Grew Its Pasadena Presence
The design leans toward comfort as well as capacity. Spacious waiting areas and thoughtful touches aim to lower the stress of a medical visit. Care that feels calmer is easier to keep up with over time.
For Pasadena and nearby towns, having USC-level care nearby is the real win. Advanced imaging, cancer-related treatment, and specialty clinics now sit minutes away. That closeness can make a hard health season a little easier to manage.
What Care Lives at Each Location
Here is a simple split:
- Imaging and scans (PET, MRI, CT, ultrasound, X-ray): 590 S. Fair Oaks
- Radiation therapy and pain management: 590 S. Fair Oaks
- Dermatology, endocrinology, and internal medicine: 625 S. Fair Oaks
- Gastroenterology, neurology, and ENT care: 625 S. Fair Oaks
- Eye care through the USC Roski Eye Institute: 625 S. Fair Oaks
Keck’s Pasadena team also reaches into surgical specialties. Patients can see specialists for vascular surgery and for hepatobiliary care, which covers the liver, gallbladder, bile ducts, and pancreas. Your referring doctor can point you to the right suite for a consultation.
The upside of two nearby buildings is choice under one health system. Your records, scans, and specialists all connect behind the scenes. That makes it simpler to move from a test to a treatment without starting over.
Imaging and Scans in Pasadena
The 590 site handles the heavier imaging needs. PET and CT scans, radiation treatments, and pain management all live here, backed by specialists in those tools. Having them together means a patient can often handle several steps in one trip.
Getting to a scan is not always easy, though, especially for older adults or anyone who cannot travel far. For basic imaging at home, a mobile service like Gentry Imaging brings X-ray and EKG to the patient across the Los Angeles and Ventura County area. That can bridge the gap when a trip to Fair Oaks is too much.
Seeing a Specialist and Getting Started
A local family physician such as Cleo Tsolakoglou-Williams, M.D. handles everyday care in Pasadena and can guide next steps. For patients who cannot easily get to an office, it is also possible to arrange for a doctor who makes house calls. Either way, having a steady doctor makes the whole system easier to use.
A primary doctor also keeps the pieces connected. They can gather your scan results, specialist notes, and medicine list in one place. That coordination matters most when more than one specialty is involved in your care.
Planning Your Visit
Before you go, it helps to have a few things sorted:
- The exact address, 590 or 625 S. Fair Oaks, plus your suite number
- Your appointment time and which specialty you are seeing
- A list of your current medicines and any recent test results
- Your photo ID and any cards the clinic asks you to bring
- Any referral or paperwork your doctor sent over
If you use the patient portal, log in the night before to check messages and forms. Arriving a few minutes early gives you room to park and find the right suite. Small steps like these keep the day calm.
For an older parent, a little extra planning goes a long way. Arrange a ride ahead of time and bring a family member if you can. A second set of ears helps you remember what the specialist says.
Contact and Locations
You can view hours, services, and directions on the Keck Medicine locations page. Checking the site first tells you exactly which address and suite your care lives at, so you arrive at the right place the first time.







